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10.1016/s0165-0173(02)00158-3 39 FranssonR.BotrosM.NybergF.LindebergG.SandstrmA.HallbergM

Lesions with a very low rate of bone formation have been described in patients with avascular necrosis

In this context, the in vitro alkaline single cell gel electrophoresis assay (SCGE or comet assay) has gained some attention as a potentially valuable, and complementary tool to the classical Ames test and EAT for predicting genotoxicity of NAs

With peptides, the timeline is slower and the effects are more subtle early on

Cryogenic electron microscopy (cryoEM) structural analyses revealed that E27 replaces endogenous CRL4 substrate receptors, resulting in proper positioning of STAT2 for polyubiquitylation and subsequent proteasomal destruction to inhibit host IFN signalling