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Some of the substances are already completely neutralised and can be eliminated from the body

Considering the molecular interactions and binding conformations shown in Fig

doi:10.1038/jcbfm.2014.77 pmid:24780902 Courchesne-Loyer A, Croteau E, Castellano CA, St-Pierre V, Hennebelle M, Cunnane SC (2017) Inverse relationship between brain glucose and ketone metabolism in adults during short-term moderate dietary ketosis: a dual tracer quantitative positron emission tomography study

However, the net effect depends on overall biological context, regulatory mechanisms, and timing