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Description

Thus, by inhibiting EndMT and TCF12 downregulation, NAC alleviates both increased perivascular collagen deposition and decreased interstitial collagen, restores cardiac collagen distribution balance, and reverses the cardiac function decline caused by PD-1 inhibitor

UDP-GlcNAc can also be metabolized by O-GlcNAc transferase (OGT) to reversibly add a O-GlcNAc modification to serine and threonine residues of proteins