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doi:10.1016/S0031-9422(00)91287-1

Diabetic myelopathy is a rare condition characterized by spinal cord dysfunction in diabetes patients without other identifiable causes, presenting with progressive spastic paraparesis, sensory disturbances below the lesion level, and potential bladder and bowel dysfunction

This response may be similar to that observed in toxic milk mice [26, 28] or could result from CuCl-induced toxicity, as cell viability dropped to 60% at 0.6mmol/l

Representatives of the different disciplines and specialties should be experienced in the field of DSDs

Consistent with these findings, expression of endothelial markers including genes encoding tight and adherens junction proteins PECAM1 (platelet/endothelial cell adhesion molecule 1/CD31, Pecam1 gene), claudin-5 ( Cldn5 ), occludin ( Ocln ), ZO1 ( Tjp1 gene), cadherin-1 ( Cdh1 ), and cadherin-5 ( Cdh5 ) were strongly downregulated (Fig