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Jin et al., 2023)

Exacerbated cytokine expression was also shown in another iPSC study (from PSEN1 E9 mutation patients) which also noted increased A pathology and Ca 2+ release from the endoplasmic reticulum of mutant cells (Oksanen et al., 2017)

Chuang ST, Chu P, Sugimura J, Tretiakova MS, Papavero V, Wang K et al

PMID: 35080890 Anal ChemImaging of Mitophagy Enabled by an Acidity-Reporting Probe Anchored on the Mitochondrial Inner Membrane

Bei einem Glutathion-Mangel , der meist durch oxidativen Stress entsteht, kommt es zu chronischer Erschpfung und Mdigkeit , weil nicht mehr ausreichend Zellenergie zur Verfgung steht