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Glutathione carbon dots as an intracellular reactive oxygen species scavenger for reducing cisplatininduced ototoxicity Tu 2024 VIEW Wiley Online Library Unveiling the Role of Oxidative Stress in Cochlear Hair Cell Death: Prospective Phytochemical Therapeutics against Sensorineural Hearing Loss Role of Oxidative Stress and Antioxidants in Acquired Inner Ear Disorders Frontiers Age related hearing loss in older adults: etiology and rehabilitation strategies PKM2 controls cochlear development through lactate dependent transcriptional regulation PNAS

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4,5,15 It is predominantly metabolized by CYP3A4

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10.1016/j.immuni.2017.03.019 66 MandalP

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Cancer Cell Internat

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In a randomized, double-blind, placebo-controlled trial, daily supplementation with Lactobacillus plantarum ECGC 13110402 for 12 weeks in adults with moderate hypercholesterolemia resulted in a significant reduction in LDL cholesterol and hs-CRP compared to placebo, suggesting a direct benefit of probiotics on cardiovascular risk markers in humans (Costabile et al., 2017)

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Tauroursodeoxycholic acid, an inhibitor of ERS, prevented pyroptosis in PTTG1-knockout LO2 cells, indicating a connection between ERS and pyroptosis

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