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PAMPs and DAMPs: Signal 0s that Spur Autophagy and Immunity

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doi: 10.3389/fnut.2021.685165 32

The oxidative damage and DNA damage induced by oxidative stress can also trigger apoptotic stress, leading to a reduction in cell numbers

Dose-dependent studies in macrophage models showed significant reductions in tissue inflammation, edema, and osteophyte formation with BV and melittin therapy at concentrations as low as 0.15 g/kg, highlighting its therapeutic efficacy (90)