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Bardoxolone methyl, a synthetic oleanane triterpenoid initially synthesized for oncological and anti-inflammatory purposes, has subsequently been recognized as a potent pharmacological activator of the NRF2 signaling pathway [214]

Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or References Navarro VJ, Khan I, Bjornsson E, Seeff LB, Serrano J, Hoofnagle JH

Methods: moDC were generated from peripheral blood monocytes from six healthy human donors of Denmark, stimulated with 1 M of Al-CPI, and cultured for 5 hours at 37C