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Autophagosome-lysosome fusion is independent of V-ATPase-mediated acidification

This is significant for combination protocols because it suggests that adding cagrilintide to retatrutide may not dramatically increase the gastrointestinal burden, provided the titration is managed correctly

In an article published on Monday in The Lancet , researchers from the University of Queensland call for a coordinated response to bring the health system up to speed to address the emerging public health issue of unregulated peptide use