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However, given the putative importance of neuroinflammation in this condition, we believe that the ME/CFS neuroimaging field could benefit from basing a priori targeting of brain regions of interest in the newly emerging human neuroinflammation literature recently meta-analyzed by Kraynak et al

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At week 4, 60% in LPD demonstrated 10% reduction in ALP (14.72- 39.65%) compared to 22% in SCD (11.59-23.76%) (P=0.05)

Human immunodeficiency virus transactivator protein (Tat) stimulates chemotaxis, calcium mobilization, and activation of human polymorphonuclear leukocytes: implications for Tat-mediated pathogenesis

On the other hand, MAT1 directly interacts with CYP2E1 to promote the methylation of CYP2E1 at R379 site and degradation through the proteasome pathway