[PubMed: 3550528] 205
Pre-culturing human adipose tissue mesenchymal stem cells under hypoxia increases their adipogenic and osteogenic differentiation potentials
Materials for delivering miR-26 Multiple materials have been used to deliver miR-26 (Table 3), including ADSCs, hpMSC-EVs, adeno-associated virus (AAV) [172, 173], aptamer chimeras [174], EC-derived exos (EC-exos) [175], engineered exos [176], enhancer delivery systems/hydrogels [177], exos derived from 293T cells [178], HA-SS-PGEA [179], Lamp2b-exos [180], light polyethylene glycol (PEG) chimera nanoparticles [181], a mesoporous silicon nanoparticle (MSN)-polyethylenimine (PEI)-KALA peptide system [182], anti-Glypican 3 (GPC3) single-stranded variable fragment (scFv)-modified exos [183], a poly(l-lactic acid) (PLLA) nanofibrous (NF) scaffold attached to poly(lactic-co-glycolic acid) (PLGA) microspheres [184], PLGA nanocomplexes [185], polyetherimide-conjugated PEGylated gold nanocage ternary nanocomplexes (PPHAuNCs-TNCs) [186], a PEI/Quantum dot (QD) nanoparticle delivery vehicle [187], single-wall carbon nanotubes (SWCNTs) [188], PEG hydrogels [189], self-complementary AAV serotype 8 (scAAV8) [190], skeletal muscle satellite cell-derived exos (SMSCs-exos) engineered with RVG peptide [191], RALA peptide [192], and tumor cell-derived exos (TEXs) [193]
The muscle loss associated with rapid weight reduction remains a clinically important concern, typically managed through adequate protein intake and resistance training
[DOI] [PubMed] [Google Scholar] 80.Conrad P.w., Freeman TL, Beitner-Johnson D, Millhorn DE
