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The reaction is very common and temporary, but simple remedies like rest and ice can help manage the discomfort

One critical caveat: animal LD50 studies do not guarantee human safety

Speak to your doctor if you get any Wegovy side effects, especially if they: Most Wegovy side effects can be managed at home by: For specific advice on your side effects, you can find more about Wegovy side effects in our guide, including tips on managing them, or ask your doctor

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In the phase 2 trial of cagrilintide 2.4 mg co-administered with semaglutide 2.4 mg (CagriSema) in people with type 2 diabetes, the combination improved glycemic control and body weight relative to semaglutide alone, consistent with amylin adding a postprandial glucose-lowering contribution on top of GLP-1 action