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At Week 18, the mean relative change from baseline in LFC was -28.1% for Chiglitazar 48 mg (p = 0.004) and -39.5% for Chiglitazar 64 mg (p 60% of tested mice

This regulation is absent in c-Met-deficient primary mouse hepatocytes, leading to the overproduction of ROS, increased oxidative stress, and heightened sensitivity to apoptosis-promoting agents

Preclinical research in diabetic neuropathy models reported protective effects through improved local blood flow and reduced oxidative stress, reinforcing the documented neurological scope of BPC-157