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coli , has been proposed as a key enzyme for the third major metabolic pathway of carnitine to TMA conversion (Koeth et al., 2014)

Gut microbiota functions: metabolism of nutrients and other food components

Mar 1 2021;282:858-868

Stocchi, F

By contrast, the more hydrophilic ursodeoxycholic acid which is present in small amounts in human bile, but can be given orally in patients with pure cholesterol gallstones, promotes gallstone dissolution by inducing a liquid crystalline mesophase in bile [8082]