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Increasing evidence indicates that PSC activation plays an important role in the progression of islet fibrosis in T2DM patients and animal models [7, 33, 34]

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This disruption of mitochondrial function and activation of apoptotic pathways ultimately boosts the anti-cancer efficacy

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Huang and colleagues observed that exposure to PS-NPs leads to intracellular ATP depletion, which activates AMPK and subsequently promotes ULK1 phosphorylation

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As expected, pVC increased the secretion of IFN- by CD4 T cells, while 1,25(OH) 2 D 3 completely suppressed IFN- secretion

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