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& Lu, P

Under pathological conditions, factors such as alcohol, bile acids, and cholecystokinin stimulate the release of Ca 2+ from the ER, resulting in intracellular calcium overload

1993;32(13):3368-3376.[DOI] 20

Archived from the original on 19 June 2024

In addition to oxidative stress, excessive copper ion accumulation alters energy metabolism patterns within cardiomyocytes by inducing abnormal aggregation of thioctylated proteins and loss of iron-sulfur cluster proteins in the respiratory chain complex through direct binding to thioctylated proteins in the mitochondrial TCA cycle (76)