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171 In recent years, a 5-LOX inhibitor upstream of LTB4 has been under development for bronchial asthma, but current 5-LOX inhibitors have problems such as lack of selectivity, structureactivity relationships, methaemoglobin formation, and poor efficiency and oral availability

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Microglial TAK1 promotes neurotoxic astrocytes and cognitive impairment in LPS-induced hippocampal neuroinflammation

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Inbreeding can result from the repeated breeding of specific animals to preserve certain desirable characteristics of a particular breed