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PD-L1 protects tumor-associated dendritic cells from ferroptosis during immunogenic chemotherapy

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Some studies suggest that prolonged or excessive mTOR inhibition may impair muscle protein synthesis and potentially exacerbate sarcopenia in older adults, highlighting a possible trade-off between metabolic benefits and preservation of lean massan area requiring further investigation [28]

These effects are caused by boosting L-arginine and NO production, leading to enhanced vasodilation, improved endothelial function, and increased muscle blood flow and oxygenation