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Description

The role of microglia in amyloid clearance from the AD brain

The intracellular sequestration and the paucity of free extracellular haem-iron ensures that there is scarce availability of this essential nutrient for pathogens ( Figure 1 Iron levels are suspected to be low in the upper respiratory tract, with an estimated daily exposure of approximately 10-25 g or around 1/1000th of that encountered by the gastrointestinal tract (Smith and McCulloh, 2015