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Proc Natl Acad Sci U S A 115:1164311648

Journal of Molecular Neuroscience 44: 611

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Urgent referral (two-week wait) is required for mouth ulcers persisting for more than three weeks, as per NICE suspected cancer guidelines

Fe 2+ , free iron ions, forms an unstable iron pool (LIP) in cells, which is transferred to mitochondria and participates in the formation of iron-dependent protein complexes, iron-sulfur clusters, heme, and other metabolic processes