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PMID: 39199558 Cancers (Basel) FAK Inhibitor-Based Combinations with MEK or PKC Inhibitors Trigger Synergistic Antitumor Effects in Uveal Melanoma

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Local SNc injections of wild-type or mutated (e.g., A53T or A30P) syn can lead to efficient transduction of TH-positive neurons in rats with progressive development of LN- and LB-like inclusions, 3080% DA cell loss, 4050% reduction in DA transmission, and reduced motor function [62]

As the data rely on self-reported inputs, there are inherent uncertainties in the individual response, but at a group level, it should provide a solid base for interpretations