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J Comput Aided Mol Des 31:201211 Lolok N, Sumiwi SA, Muhtadi A, Susilawati Y, Hendriani R, Ramadhan DS, Levita J, Sahidin I (2022) Molecular docking and molecular dynamics studies of bioactive compounds contained in noni fruit Morinda citrifolia L

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Although the primary behavioral outcomes of addictive substances are realized through distinct effector mechanisms, such as neurotransmitter transporters, ion channels, and receptor proteins, the common feature of these drugs is concerned with increased dopamine neurotransmission within the mesocorticolimbic circuitry of the brain from the ventral tegmental area to the nucleus accumbens and prefrontal cortex [1]

The cysteine residue in the molecule center is liable for the high reduction potential of GSH