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Progressive Symptoms if Left Untreated If B12 deficiency is not treated, symptoms can get worse

Abstract Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease globally

Diabetes Care 45(4):811818 Sugawara Y, Kanazawa A, Aida M, Yoshida Y, Yamashiro Y, Watada H (2022) Association of gut microbiota and inflammatory markers in obese patients with type 2 diabetes mellitus: post hoc analysis of a synbiotic interventional study

Analysis of mtDNA methylation was also performed in platelets from CVD patients, where an increase in 5mC methylation was found in comparison with healthy controls (89)

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