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At therapeutic GHK-Cu doses, copper accumulation is not a clinical concern for healthy individuals but it is why medical oversight matters

Skin Barrier Repair Models In barrier-disruption models, GHK-Cu has been reported to support recovery of stratum-corneum lipid composition and tight-junction protein expression [6]

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Investigations are guided by clinical suspicion rather than routine panels: for example, thyroid function tests and ferritin may be checked if symptoms suggest deficiency or thyroid disease, while an androgen profile may be appropriate in women presenting with menstrual irregularity, hirsutism, or acne