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Transparency and Informed Consent: The clinic should provide clear information about the procedure, its potential benefits, risks, and expected outcomes

Proteins 15, 443450

All cell types were cultured by regular passages in media supplemented with 10% fetal bovine serum (Gibco, Waltham, MA, USA) at 37C in a humidified atmosphere containing 5% CO2

Although this possibility cannot be excluded in principle, current experimental evidence remains insufficient, and further mechanistic investigation is needed

A pharmaceutical composition according to the present invention may be especially beneficial in conferring stability to the activatable antibody construct where the pi of the at least two masking moieties of the at least two binding domains differ