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Readers are encouraged to refer to other relevant reviews that focus on this important area 31,32,33

We discovered that HSA, IgG and the majority of other human plasma proteins are transformed into potent inducers of the neutrophil respiratory burst specifically by N-chlorination [37], the same mechanism by which bacteria were found to employ novel chaperones to protect their proteins against HOCl-stress-induced aggregation [15, 16] (Fig