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Normothermic ex vivo machine perfusion for liver transplantation: a systematic review of progress in humans

In addition, the OCR was higher under normal glucose than under high glucose conditions, suggesting that mitochondria-targeted therapy is more effective under normal glucose conditions than under high glucose conditions 9 , with a glucose concentration of 1000 mg/L being considered normal in humans

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Additionally, studies have shown that the combination of fosfomycin and -lactams leads to a more pronounced reduction in the functional expression or activity of PBPs, further elucidating the mechanistic basis for their synergistic antibacterial effect ( FIGURE 2 4.1.1 Combinations with carbapenems Carbapenems (such as meropenem and imipenem) are considered last-resort antibiotics for treating bacterial infections