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Cadmium, in particular, damages mitochondria, reducing energy production.53 Heavy metals enter the body through contaminated food, water, alcohol, smoking, fumes, or skin contact

Patients with dissection (n = 125) had significantly increased values of ICA tortuosity compared to healthy controls (n = 24) (OR 2.65[CI 1.68-3.86], p 100 mmHg) at randomization

Insulin resistance in polycystic ovary syndrome across various tissues: An updated review of pathogenesis, evaluation, and treatment

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In the ETC, complexes donate electrons to oxygen producing radicals like superoxide and peroxidases, and high levels of such radicals and oxidative stress cause damage to lipids, enhance DNA breaks, and oxidize nuclear and mtDNA (Tobe, 2013