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doi: 10.3389/fendo.2021.627167 Received 08 November 2020 Accepted 03 March 2021 Published 19 March 2021 Volume 12 - 2021 Edited by Virginia Lorenz, National University of Littoral, Argentina Reviewed by Jun Yoshinaga, Toyo University, Japan

A full blood count may reveal macrocytic anaemia (enlarged red blood cells) with elevated mean corpuscular volume (MCV), though this finding is not specific to B12 deficiency and can occur in liver disease independently