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These cells - mainly blood and gut cells - are all replaced with new ones, but the way our bodies rid themselves of material could have profound implications for cancer therapies in a new approach developed by Stanford Medicine researchers

doi: 10.1002/ana.24369, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] Sevigny J., Chiao P., Bussire T., Weinreb P

The HO-1/NQO-1 pathway inhibits COX-2 expression, thereby suppressing the expression and secretion of the inflammatory factors interleukin-1 (IL-1), IL-6, interleukin-8 (IL-8), interleukin-25 (IL-25), and interleukin-33 (IL-33)

Additionally, M2-associated iron recycling pathways (HMOX1 upregulation, heme metabolism) can be targeted to shift intracellular iron pools toward pro-ferroptotic states

A dietary pattern characterized by a high consumption of red and/or processed meat, refined grains, sweets, high-fat dairy products, butter, potatoes and high-fat sauces and a low consumption of fruits and vegetables is associated with an increased risk of depression