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Updated February, 2008

By directly binding to SLC7A11, recombinant human autophagy effector protein (BECN1) inhibits the activity of system x c , promotes GSH consumption and lipid peroxidation, and induces ferroptosis in cancer cells [137]

Health benefits of medicinal plant natural products via microbiota-mediated different gut axes

Breivogel CS, Puri V, Lambert JM, Hill DK, Huffman JW, Razdan RK

In pathophysiological states, including increased insulin resistance, the hybrid receptor number is changed significantly, thus potentially abrogating the chance for IGF-1 to alter glucose metabolism [129, 132, 133]