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This so-called autocrine loop of ROS by HSCs is regarded as mechanism corresponding to the autocrine loop of TGF- which HSCs produce in response to this cytokine with an increased collagen expression in the injured liver (Itagaki et al., 2005)

Owing to the high rate of comorbidity between motor speech dysfunction and the neurological control centers of post-stroke swallowing disorders, similar pathological mechanisms between the two have been observed, and the crossover between the two has potential clinical applications

Two studies on athletes showed that exogenous administration of melatonin can alleviate oxidative stress, inflammation, and muscle damage, and might improve exercise performance 60,61

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