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Premise and prediction how optic nerve head biomechanics underlies the susceptibility and clinical behavior of the aged optic nerve head

In acute myeloid leukemia (AML), gold nanoparticles (AuNPs) were modified by encapsulating anti-miR-221 and adding to their surfaces DNA aptamer AS1411, which can interact specifically with nucleolin in AML cells, thereby targeting the nucleolin/miR-221/NF-B/DNMT1 signaling pathway responsible for leukemogenesis (Deng et al