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Description

Tamoxifen is used as the low solubility control and caffeine as the high solubility control, providing reference points to bracket the assay range and verify assay performance

It also resulted in a 13.2% decrease in body weight in an East Asian population with overweight or obesity, with or without T2DM

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The trial enrolled adults with overweight or obesity and randomised them to receive CagriSema, cagrilintide alone, semaglutide alone, or placebo over 32 weeks