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This page was last updated at 9:44AM on June 2, 2026

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Materials and Methods Isolation and in vitro Expansion of Human Chondrocytes Human chondrocytes were isolated from de-identified knee articular cartilage without signs of osteoarthritis or injury

Meanwhile, NNMTi preserves lean body mass: it reduces fat accumulation without causing muscle loss, which is crucial for maintaining basal metabolism and preventing weight regain after dieting.These in vivo findings fully validate the efficacy and safety of NNMTi in obesity intervention, laying a solid foundation for its subsequent clinical research and drug development