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Taken together, the stabilization of HIF-1 promotes pathogen clearance in mycobacterial infection by the remodeling of metabolic pathways in macrophages, and the effect of HIF-1 can be beneficial or detrimental to the host depending on the infection stages or immune cell activation states ( Table 3 )

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Although it cannot yet be determined whether vitamin B 12 deficiency plays a causal role in depression, it may be beneficial to screen for vitamin B 12 deficiency in older individuals as part of a medical evaluation for depression

Instead, it recognizes the material and allows it to pass through the intestinal wall with ease