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Rotter et al

From six months to five years, the bleeding risk was similar

ML162 and RSL3 were administered subcutaneously or intratumorally, as they are known to have poor solubility and therefore limited systemic effect 48

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In addition, the ZFPG + US treatment down-regulated the expression of the fatty acid synthase ( FASN ) gene, which could enhance the occurrence of ferroptosis by altering lipid metabolism and increasing lipid peroxidation (Figs