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This is why B12 injections can be so effectivethey bypass the digestive system entirely, delivering the vitamin directly where your body can use it

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Treatment typically involves vitamin B12 supplementation, either through oral supplements or injections, depending on the severity of the deficiency and underlying causes.

Doses above 100mg daily show diminishing returns in NNMT inhibition the enzyme inhibition curve plateaus beyond 150mg while increasing the risk of methylation pathway disruption and homocysteine elevation