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Compared with other pathological types, the mesenchymal molecular subtype of ovarian cancer tends to have higher NNMT expression

They analyze how this compound may influence pathways associated with energy balance, cellular signaling, and metabolic activity

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Modulation of the immunosuppressive tumor microenvironment The BM niche in MM patients is intrinsically immunosuppressive, containing cells able to blunt the immune response and adenosine (ADO) that may lead to an anergic status of T, NK, and dendritic cells [10]

2.4 Combining DPI, MitoQ and vincristine induces cell death of MNA NB cells To characterize the interaction between MitoQ, DPI, and vincristine, we assessed their effects on cell death at IC50/2 and IC50/3 concentrations in four NB cell lines: Be(2)-C (MNA), IMR-32 (MNA), IMR-5/75 (MNA with MYCN downregulatable), and SH-SY5Y/MYCN (non-MNA, MYCN-inducible)