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Decreased expression of adhesion molecules, such as endothelial-leucocyte adhesion molecule-1 (E-selectin), intercellular adhesion molecule-1 and vascular cell adhesion molecule-1, has been observed in human aortic endothelial cells cultured with ergothioneine (Reference Martin90)

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10.1016/j.jtcme.2019.02.004 130 LuJ.MaY.WuJ.HuangH.WangX.ChenZ.et al (2019)

B12 is necessary for your bodys functioning in the brain, nerves, blood cells and more

Hence, the combination of ferroptosis and ICIs could be a new exploration for reducing ICIs resistance and ultimately broaden the pool of patients potentially benefiting from ICIs (Table 3)