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10.1002/mrm.22093 Summary Keywords intervertebral disc degeneration, lactate, lactylation, metabolism, functions, intervention strategies Citation Liu Y, Yang J, Wang Z, Fu J, Liu H, Lu Z, Dong J, Li Z, Mao Q, Li C and Ma H (2025) Lactate and lactylation in intervertebral disc degeneration

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GAL1p-PGI1t was obtained after OE-PCR, digested by Hin dIII and Not I and eventually subcloned with linearized pRS413 (his3 auxotrophic marker), resulting in the GAL1p expression cassette

Its advisable to start with lower dosages and gradually increase as needed while monitoring for any adverse effects