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Exercise Recovery and Stress Adaptation When you push your body, whether through an intense workout, a demanding climb or long hours of travel, your cells generate more free radicals, increasing oxidative stress

In this case, the rs2268277 SNP is located at a runt-related transcription factor 1 (RUNX1) binding site located in intron 6 of the SLC22A4 gene (Reference Tokuhiro, Yamada and Chang58)

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It also induced polarization of M1 macrophages, resulting in decreased expression of IL-1 and IL-6, while promoting the production of M2 macrophages