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The liver is the primary target organ for iron overload, and notable iron accumulation led to liver dysfunction in this patient

doi: 10.1007/s12020-011-9472-3 34 BartalenaLTandaMLPiantanidaELaiA

MBalara K, Henry C, Lestage J, Launay JM, Parrot F, Swendsen J, et al

HBP activity exerts context-dependent effects: acute activation may offer cardioprotection, whereas chronic HBP upregulation under hyperglycemia induces endoplasmic reticular (ER) stress, lipid accumulation, and inflammation [72]