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It modulates the nitric oxide (NO) system in a bidirectional manner, meaning it can counteract both NO-excess states (like those caused by L-arginine or NO donors) and NO-deficiency states (such as those induced by L-NAME)

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Current medicinal chemistry , 19 1, 126-32

[30] This effect may be due to the strong coordination between benzimidazole and the central cobalt atom, pulling it down into the plane of the corrin ring