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Turk J Biol

Introduction Cataracts Cataracts, characterized by progressive opacification of the ocular lens, are the leading cause of visual impairment and blindness worldwide (1)

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2 Characteristic of early disease stage

For example, kynurenine restrains melanoma and endothelioma cellular proliferation [136, 137], impairing DNA synthesis and inducing necrosis in melanoma cells, while promoting the -catenin pathway and colon cancer cells multiplication in a dose-dependent manner [138]