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Specific markers for ferroptosis include oxidized polyunsaturated fatty acid phospholipids and their breakdown products, as well as oxidative compounds such as 4-HNE, 8-hydroxy-2-deoxyguanosine (8-OHdG), and MDA

Br J Pharmacol 2016;173:6676 [DOI] [PMC free article] [PubMed] [Google Scholar] 85.Bateman DN, Dear JW, Thanacoody HK, Thomas SH, Eddleston M, Sandilands EA, Coyle J, Cooper JG, Rodriguez A, Butcher I, Lewis SC, Vliegenthart AD, Veiraiah A, Webb DJ, Gray A.Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial

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CD38-specific sdAbs, such as sdAb 2F8, characterized by our laboratory, showing excellent tumor targeting and their engineered constructs, such as biparatopic antibodies and chimeric antibodies, represent a new generation of theranostic agents for diagnosis and treatment CD38-expressing malignancies

The administration of mitochondria-targeted antioxidants is one of the drug delivery systems targeted to mitochondria