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We next visualized the same paired loci in the cnd1-K658E mutant and found that the shortening of the intra-domain probe distances observed in wild-type cells during mitosis was significantly compromised in the mutant, indicating that domain-based chromosome compaction during mitosis is impaired in the cnd1-K658E mutant (Fig

27 Under hypoxic conditions, intervened by hypoxia-inducible factor (HIF), there is a reduction in hepcidin expression, which promotes iron release