foxo4-dri senolytic peptide study 2017 cell Frontiers The disordered p53 transactivation domain
The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications CHK2 USP37 axis stabilizes FOXO4 to sustain senescence and evade apoptosis PNAS Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging: Cell Full article: Targeting Cellular Senescence for Healthy Aging: Advances in Senolytics and Senomorphics FOXO4 DRI alleviates age related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice Aging
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