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Increased Serum Sclerostin and Decreased Serum IGF-1 Are Associated With Vertebral Fractures Among Postmenopausal Women With Type-2 Diabetes

The COFU3 Study

Further evaluation, including electrocardiography, echocardiography, and carotid echo-Doppler examination, can be performed if clinically indicated (23)

Correct site selection helps ensure effective medication absorption and reduces the risk of nerve injury, vascular damage, and injection-related complications

Antimicrobial agents also change intestinal microbiota that may alter the balance in the production of SCFAs vital for the physiologic development of intestinal mucosal functions