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1994 The severity of growth hormone deficiency in adults with pituitary disease is related to the degree of hypopituitarism

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The amino acid sequence and specific modifications in its chemical structure determine its ability to selectively stimulate the release of growth hormone, while avoiding some adverse reactions that traditional drugs may cause, such as increased appetite, elevated prolactin, and elevated cortisol

This release of secondary messenger molecules such as IP3 might potentially stimulate the discharge of calcium ions (Ca2+) from the cell's internal stores, while DAG might activate protein kinase C (PKC)

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